The MED12 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to MED12. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The MED12 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway